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oxysterol 7-alpha-hydroxylase MeSH Supplementary Concept Data 2024


MeSH Supplementary
oxysterol 7-alpha-hydroxylase
Unique ID
C115867
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C115867
Entry Term(s)
25-HC 7alpha-hydroxylase
25-hydroxycholesterol 7-alpha-hydroxylase
25-hydroxycholesterol 7alpha-hydroxylase
3 beta-hydroxysteroid 7-alpha-hydroxylase
3 beta-hydroxysteroid-7 alpha-hydroxylase
5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase
5alpha-androstane-3beta,17beta-diol 7-alpha-hydroxylase
DHEA 7-alpha-hydroxylase
dehydroepiandrosterone 7-alpha-hydroxylase
dehydroepiandrosterone 7-hydroxylase
oxysterol 7 alpha-hydroxylase
Registry Number
EC 1.14.13.-
Related Numbers
2E7DZF35YK
EC 1.14.-
Previous Indexing
*CYTOCHROME P-450 ENZYME SYSTEM (1998-2008)
Heading Mapped to
*Steroid Hydroxylases
Frequency
48
Note
a widely distributed P-450 enzyme found in brain, testis, ovary, prostate, liver, colon, kidney, and small intestine; catalyzes 7-alpha-hydroxylation of a broad spectrum of substrates including dehydroepiandrosterone, pregnenolone, 25- or 27-hydroxycholesterol; is important in bile acid synthesis; mutation of CYP7B1 gene causes severe neonatal giant cell HEPATITIS
Source
J Clin Invest 1998 Nov 1;102(9):1690-703
Date of Entry
1998/12/11
Revision Date
2018/12/20
oxysterol 7-alpha-hydroxylase Preferred
dehydroepiandrosterone 7-hydroxylase Broader
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