MeSH Browser

MeSH Supplementary: oxysterol 7-alpha-hydroxylase
Unique ID: C115867
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C115867
Entry Term(s): 25-HC 7alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7alpha-hydroxylase; 3 beta-hydroxysteroid 7-alpha-hydroxylase; 3 beta-hydroxysteroid-7 alpha-hydroxylase; 5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase; 5alpha-androstane-3beta,17beta-diol 7-alpha-hydroxylase; DHEA 7-alpha-hydroxylase; dehydroepiandrosterone 7-alpha-hydroxylase; dehydroepiandrosterone 7-hydroxylase; oxysterol 7 alpha-hydroxylase
Registry Numbers: EC 1.14.13.-; EC 1.14.-
Related Numbers: 2E7DZF35YK; EC 1.14.-
Previous Indexing: *CYTOCHROME P-450 ENZYME SYSTEM (1998-2008)
Heading Mapped to: *Steroid Hydroxylases
Frequency: 48
Note: a widely distributed P-450 enzyme found in brain, testis, ovary, prostate, liver, colon, kidney, and small intestine; catalyzes 7-alpha-hydroxylation of a broad spectrum of substrates including dehydroepiandrosterone, pregnenolone, 25- or 27-hydroxycholesterol; is important in bile acid synthesis; mutation of CYP7B1 gene causes severe neonatal giant cell HEPATITIS
Source: J Clin Invest 1998 Nov 1;102(9):1690-703
Date of Entry: 1998/12/11
Revision Date: 2018/12/20

oxysterol 7-alpha-hydroxylase MeSH Supplementary Concept Data 2025