MeSH Browser

MeSH Heading: Complement C4a
Tree Number(s): D12.776.124.486.274.024.260; D12.776.124.486.274.350.250
Unique ID: D015934
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015934
Scope Note: The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.
Entry Term(s): C4a Complement; Complement 4a; Complement Component 4a
Pharm Action: Immunologic Factors
Registry Number: 80295-49-4
CAS Type 1 Name: Complement C4a
Previous Indexing: Anaphylatoxins (1980-1982); Complement 4 (1978-1989)
Public MeSH Note: 2006; see COMPLEMENT 4A 1990-2005
History Note: 2006 (1990)
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024379
Registry Number: 80295-49-4
Scope Note: The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.
Terms: Complement C4a Preferred Term
Term UI T622686
Date12/08/2004
LexicalTag NON
ThesaurusID NLM (2006); Complement Component 4a
Term UI T622687
Date12/08/2004
LexicalTag NON
ThesaurusID NLM (2006); C4a Complement
Term UI T631379
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Complement 4a
Term UI T047280
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990)

Complement C4a MeSH Descriptor Data 2024