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Cyclin-Dependent Kinase 2 MeSH Descriptor Data 2022


MeSH Heading
Cyclin-Dependent Kinase 2
Tree Number(s)
D08.811.913.696.620.682.700.646.500.750
D12.776.167.200.323
D12.776.476.563.646.500.750
Unique ID
D051357
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051357
Scope Note
A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
Entry Term(s)
CDK2 Protein
Cdc2-Related Protein Kinase
Cdk2 Protein Kinase
p33cdk2 Kinase
Registry Number
EC 2.7.11.22
Public MeSH Note
2006; CYCLIN-DEPENDENT KINASE 2 was indexed under CDC2-CDC28 KINASES 2004-2005, & under CYCLIN-DEPENDENT KINASES 1991-2003, & under PROTEIN KINASES 1991-1994
History Note
2006(1991)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
Cyclin-Dependent Kinase 2 Preferred
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