MeSH Browser

MeSH Supplementary: fibrolase
Unique ID: C058789
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C058789
Entry Term(s): Agkistrodon contortrix fibrin-degrading metalloprotease
Registry Numbers: EC 3.4.24.-
Heading Mapped to: *Metalloendopeptidases
Frequency: 34
Note: from the venom of Agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; MW 23-25kDa; cleaves primarily the Aa-chain of human fibrinogen & fibrin between the Lys-413 & Leu-414 position; the Bb chain is cleaved more slowly; gamma chain is minimally affected
Source: Thromb Res 1988;52(6):541
Date of Entry: 1989/04/18
Revision Date: 2001/05/22

fibrolase MeSH Supplementary Concept Data 2025