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Long-Term Synaptic Depression MeSH Descriptor Data 2025


MeSH Heading
Long-Term Synaptic Depression
Tree Number(s)
G11.561.638.355
Unique ID
D036881
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D036881
Annotation
note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS
Scope Note
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Entry Term(s)
Depotentiation
Homosynaptic Depression
Long-Term Depression, Neurophysiologic
Long-Term Depression, Neurophysiological
Long-Term Depression, Physiologic
Long-Term Depression, Physiological
NLM Classification #
WL 102
Previous Indexing
Neuronal Plasticity (1985-2002)
Public MeSH Note
2008; see LONG-TERM DEPRESSION (PHYSIOLOGY) 2003-2007
History Note
2008 (2003)
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/06/23
Long-Term Synaptic Depression Preferred
Depotentiation Related
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