MeSH Browser

MeSH Heading: Lysine Carboxypeptidase
Tree Number(s): D08.811.277.656.350.245.450; D08.811.277.656.350.555.750; D08.811.277.656.675.555.750
Unique ID: D001121
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001121
Scope Note: A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is a plasma zinc enzyme that inactivates bradykinin and anaphylatoxins.
Entry Term(s): Anaphylatoxin Inactivator; Bradykininase; Carboxypeptidase N; Kininase I
Registry Number: EC 3.4.17.3
Previous Indexing: Arginine (1972-1974); Carboxypeptidases (1972-1974); Peptides (1972-1974)
Public MeSH Note: 1997; see ARGININE CARBOXYPEPTIDASE 1991-1996, see CARBOXYPEPTIDASES 1975-1990; for KININASE I see CARBOXYPEPTIDASES 1975-1981
History Note: 1997 (1975)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0001685
Registry Number: EC 3.4.17.3
Scope Note: A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is a plasma zinc enzyme that inactivates bradykinin and anaphylatoxins.
Terms: Lysine Carboxypeptidase Preferred Term
Term UI T003393
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Bradykininase
Term UI T003390
Date02/17/1983
LexicalTag NON
ThesaurusID UNK (19XX); Kininase I
Term UI T003392
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX); Anaphylatoxin Inactivator
Term UI T003387
Date08/12/1987
LexicalTag NON
ThesaurusID UNK (19XX); Carboxypeptidase N
Term UI T003391
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Lysine Carboxypeptidase MeSH Descriptor Data 2024