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MHC class II transactivator protein MeSH Supplementary Concept Data 2024


MeSH Supplementary
MHC class II transactivator protein
Unique ID
C083728
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C083728
Entry Term(s)
C2TA protein, human
C2ta protein, mouse
CIITA protein, human
CIITA protein, mouse
MHC class II transactivator protein, human
MHC2TA protein, human
Mhc2ta protein, rat
class II transactivator
class II transactivator protein, mouse
Registry Number
0
Heading Mapped to
*Nuclear Proteins
*Trans-Activators
Frequency
787
Note
a major histocompatibility complex class II transactivator; essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter; defects in MHC2TA are a cause of BARE LYMPHOCYTE SYNDROME type II (BLS II), a severe form of SCID; RefSeq NM_000246 (human); NM_007575 (mouse)
Source
Cell 1993 Oct 8;75(1):135-46
Indexing Information
Genes, MHC Class II
Date of Entry
1993/11/16
Revision Date
2012/08/30
MHC class II transactivator protein Preferred
MHC2TA protein, human Narrower
Mhc2ta protein, rat Narrower
C2ta protein, mouse Narrower
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