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continuous erythropoietin receptor activator MeSH Supplementary Concept Data 2023


MeSH Supplementary
continuous erythropoietin receptor activator
Unique ID
C508420
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C508420
Entry Term(s)
CERA (erythropoietin receptor activator)
Mircera
epoetin beta pegol
methoxy polyethylene glycol-epoetin beta
Registry Number
0
Previous Indexing
*Erythropoietin (2006-2010)
Heading Mapped to
*Erythropoietin
*Polyethylene Glycols
Frequency
180
Note
a third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia
Source
Curr Hematol Rep 2005 Nov;4(6):436-40
Date of Entry
2006/03/06
Revision Date
2016/07/12
continuous erythropoietin receptor activator Preferred
methoxy polyethylene glycol-epoetin beta Related
Mircera Narrower
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