MeSH Browser

MeSH Supplementary: o-succinylbenzoic acid synthase
Unique ID: C052986
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C052986
Entry Term(s): 2-succinylbenzoic acid synthase; MenC protein, E coli; OSB synthase; o-succinylbenzoate synthase; ortho-succinylbenzoic acid synthase
Registry Number: EC 4.1.99.-
Previous Indexing: *LYASES (87-97)
Heading Mapped to: *Carbon-Carbon Lyases
Frequency: 24
Note: E coli enzyme; with SHCHC synthase catalyzes formation of o-succinylbenzoic acid from isochorismic acid & alpha-ketoglutarate in presence of thiamine pyropyrophosphate; succinic semialdehyde anion is formed by decarboxylation of alpha-ketoglutarate by thiamine pyrophosphate; anion then attacks isochorismic acid, initiating aromatization with elimination of pyruvate & H2O
Source: Arch Biochem Biophys 1987;256(1):212
Date of Entry: 1987/08/24
Revision Date: 2009/02/05

o-succinylbenzoic acid synthase MeSH Supplementary Concept Data 2024