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gedatolisib MeSH Supplementary Concept Data 2023


MeSH Supplementary
gedatolisib
Unique ID
C549060
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C549060
Entry Term(s)
1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea
PF-05212384
PKI 587
PKI-587
PKI587
Pharm Action
Protein Kinase Inhibitors
Registry Number
96265TNH2R
Heading Mapped to
*Morpholines
*Triazines
Frequency
38
Note
inhibits both phosphatidylinositol 3-kinase and mTOR; structure in first source
Source
J Med Chem 2010 Mar 25;53(6):2636-45
Date of Entry
2010/05/02
Revision Date
2018/09/24
gedatolisib Preferred
PKI 587 Narrower
PF-05212384 Narrower
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