MeSH Browser

MeSH Heading: Peroxisomal Disorders
Tree Number(s): C16.320.565.663; C18.452.648.663
Unique ID: D018901
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018901
Annotation: general or unspecified; prefer specifics; do not confuse entry term ADRENOLEUKODYSTROPHY, NEONATAL with ADRENOLEUKODYSTROPHY
Scope Note: A heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional PEROXISOMES. Peroxisomal enzymatic abnormalities may be single or multiple. Biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. Diseases in this category include ZELLWEGER SYNDROME; INFANTILE REFSUM DISEASE; rhizomelic chondrodysplasia (CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and ADRENOLEUKODYSTROPHY (X-linked). Neurologic dysfunction is a prominent feature of most peroxisomal disorders.
Entry Version: PEROXISOMAL DIS
Entry Term(s): Adrenoleukodystrophy, Autosomal Neonatal Form; Adrenoleukodystrophy, Autosomal, Neonatal Form; Adrenoleukodystrophy, Neonatal; Hyperpipecolatemia; Hyperpipecolic Acidemia; Neonatal Adrenoleukodystrophy; Peroxisomal Dysfunction, General; Peroxisomal Dysfunction, Multiple; Peroxisomal Dysfunction, Single
NLM Classification #: QU 265.5.P4
Previous Indexing: Lipid Metabolism, Inborn Errors (1988-1995); Metabolism, Inborn Errors (1988-1995)
Public MeSH Note: 1996
History Note: 1996
Date Established: 1996/01/01
Date of Entry: 1994/12/27
Revision Date: 2015/06/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Metabolism, Inborn Errors [C16.320.565]

Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
  - Metabolism, Inborn Errors [C18.452.648]

Peroxisomal Disorders Preferred

Hyperpipecolic Acidemia Narrower

Peroxisomal Dysfunction, Multiple Narrower

Peroxisomal Dysfunction, Single Narrower

Adrenoleukodystrophy, Neonatal Narrower

Peroxisomal Dysfunction, General Narrower

Peroxisomal Disorders MeSH Descriptor Data 2024