MeSH Browser

MeSH Heading: Prostate-Specific Antigen
Tree Number(s): D08.811.277.656.300.760.442.750; D08.811.277.656.959.350.442.750; D12.776.869.250.249.500; D23.050.285.625; D23.101.140.625
Unique ID: D017430
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017430
Scope Note: A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Entry Term(s): Kallikrein hK3; Prostate Specific Antigen; Semenogelase; Seminin; gamma-Seminoprotein; hK3 Kallikrein
Registry Number: EC 3.4.21.77
NLM Classification #: WJ 762
Previous Indexing: Antigens, Neoplasm (1982-1992)
See Also: Prostatic Neoplasms
Public MeSH Note: 93; PROSTATE CANCER SPECIFIC ANTIGENS was indexed under ANTIGENS, NEOPLASM 1982-92; SEMENOGELASE was indexed under PROSTATE-SPECIFIC ANTIGEN 1988-95 & PEPTIDE PEPTIDOHYDROLASE 1976-87
Online Note: use PROSTATE-SPECIFIC ANTIGEN (NM) to search PROSTATE CANCER SPECIFIC ANTIGENS 1982-92 & SEMENOGELASE 1980-95
History Note: 93; was PROSTATE CANCER SPECIFIC ANTIGENS (NM) 1982-92; SEMENOGELASE was NM 1976-95
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2022/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0026444
Registry Number: EC 3.4.21.77
Scope Note: A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Terms: Prostate-Specific Antigen Preferred Term
Term UI T052144
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993); gamma-Seminoprotein
Term UI T052142
Date02/03/1995
LexicalTag NON
ThesaurusID NLM (1996); Prostate Specific Antigen
Term UI T052143
Date03/26/1992
LexicalTag NON
ThesaurusID NLM (1993); hK3 Kallikrein
Term UI T052147
Date02/13/1998
LexicalTag NON
ThesaurusID NLM (1999); Semenogelase
Term UI T052145
Date02/03/1995
LexicalTag NON
ThesaurusID NLM (1996); Kallikrein hK3
Term UI T052146
Date02/13/1998
LexicalTag NON
ThesaurusID NLM (1999); Seminin
Term UI T052141
Date02/03/1995
LexicalTag NON
ThesaurusID NLM (1996)

Prostate-Specific Antigen MeSH Descriptor Data 2024