MeSH Browser

MeSH Heading: SEC Translocation Channels
Tree Number(s): D05.500.890.625; D12.776.157.530.875; D12.776.543.585.875
Unique ID: D000069816
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069816
Scope Note: Universally conserved multiprotein complexes that form the protein transport channel of the general secretory (SEC) pathway. The SEC translocase is present in all bacteria, archaea, and eukaryotes. It is in the ENDOPLASMIC RETICULUM membrane of eukaryotic cells, in the THYLAKOID MEMBRANE in CHLOROPLASTS and in some protozoa in the INNER MITOCHONDRIAL MEMBRANE.
Entry Term(s): SEC Complexes; SEC Translocase; SEC Translocation Channel; SEC Translocon; SEC Translocons; SEC61 Protein; SEC61 Proteins; SEC61 Translocase; SEC61 Translocation Channel; SEC61 Translocation Channels; SEC61 Translocon; Sec Protein Translocation System; Sec Protein Translocation Systems; Sec61 Complex; Sec61 Protein Translocation System; SecY Translocase; SecYEG Complex; SecYEG Complexes; SecYEG Protein; SecYEG Protein Translocation System; SecYEG Proteins; SecYEG Translocation Channel; SecYEG Translocation Channels; SecYEG Translocon
Registry Number: 0
Previous Indexing: Membrane Transport Proteins (1999-2016)
Public MeSH Note: 2017; SEC61 PROTEIN was indexed under SEC TRANSLOCATION CHANNELS 2016-2017 and MEMBRANE PROTEINS 1992-2016
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000607759
Registry Number: 0
Scope Note: Universally conserved multiprotein complexes that form the protein transport channel of the general secretory (SEC) pathway. The SEC translocase is present in all bacteria, archaea, and eukaryotes. It is in the ENDOPLASMIC RETICULUM membrane of eukaryotic cells, in the THYLAKOID MEMBRANE in CHLOROPLASTS and in some protozoa in the INNER MITOCHONDRIAL MEMBRANE.
Terms: SEC Translocation Channels Preferred Term
Term UI T000883484
Date07/16/2015
LexicalTag NON
ThesaurusID NLM (2017); SEC Translocation Channel
Term UI T000997154
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); SEC Translocase
Term UI T000883488
Date07/16/2015
LexicalTag NON
ThesaurusID NLM (2017); Sec Protein Translocation Systems
Term UI T000883485
Date07/16/2015
LexicalTag NON
ThesaurusID NLM (2017); SEC Translocons
Term UI T000883486
Date07/16/2015
LexicalTag NON
ThesaurusID NLM (2017); SEC Complexes
Term UI T000883487
Date07/16/2015
LexicalTag NON
ThesaurusID NLM (2017); SEC Translocon
Term UI T000997153
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); Sec Protein Translocation System
Term UI T000997155
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021)

Concept UI: M000625120
Registry Number: 0
Scope Note: SEC translocase of bacteria and CHLOROPLAST membranes. The three subunits are SecY, SecE, and SecG.
Terms: SecYEG Translocon Preferred Term
Term UI T000913408
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SecYEG Complexes
Term UI T000913409
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SecY Translocase
Term UI T000914007
Date01/11/2017
LexicalTag NON
ThesaurusID NLM (2018); SecYEG Protein Translocation System
Term UI T000913411
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SecYEG Translocation Channels
Term UI T000913412
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SecYEG Translocation Channel
Term UI T000997159
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); SecYEG Complex
Term UI T000913410
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018)

Concept UI: M000625119
Registry Number: 0
Scope Note: The SEC translocase of ENDOPLASMIC RETICULUM membranes. The three subunits are SEC61alpha, SEC61beta, and SEC61gamma. Homologs of these subunits are also found in ARCHAEA,
Terms: SEC61 Translocon Preferred Term
Term UI T000913403
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SEC61 Translocation Channels
Term UI T000913407
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SEC61 Translocase
Term UI T000913405
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); Sec61 Complex
Term UI T000913406
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018); SEC61 Translocation Channel
Term UI T000997157
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); Sec61 Protein Translocation System
Term UI T000913404
Date12/30/2016
LexicalTag NON
ThesaurusID NLM (2018)

SEC Translocation Channels MeSH Descriptor Data 2024