MeSH Browser

MeSH Heading: Axitinib
Tree Number(s): D02.065.277.051; D02.241.223.100.100.115; D02.455.426.559.389.127.085.093; D03.383.129.539.487.065; D03.633.100.449.065
Unique ID: D000077784
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077784
Scope Note: A benzamide and indazole derivative that acts as a TYROSINE KINASE inhibitor of the VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR. It is used in the treatment of advanced RENAL CELL CARCINOMA.
Entry Term(s): AG 013736; AG-013736; AG013736; Inlyta
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: C9LVQ0YUXG
CAS Type 1 Name: Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-
Public MeSH Note: 2019; AXITINIB was indexed under IMIDAZOLES and INDAZOLES 2005-2018
History Note: 2019 (2005)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Amides [D02.065]
  - Benzamides [D02.065.277]

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Acids, Carbocyclic [D02.241.223]
    - Benzoates [D02.241.223.100]
      - Benzamides [D02.241.223.100.100]
        
        Acecainide [D02.241.223.100.100.033]
        
        Aminohippuric Acids [D02.241.223.100.100.100]
        
        Amisulpride [D02.241.223.100.100.110]
        
        Axitinib [D02.241.223.100.100.115]
        
        Bezafibrate [D02.241.223.100.100.120]
        
        Cisapride [D02.241.223.100.100.135]
        
        DEET [D02.241.223.100.100.230]
        
        Dinitolmide [D02.241.223.100.100.240]
        
        Hippurates [D02.241.223.100.100.400]
        
        Imatinib Mesylate [D02.241.223.100.100.435]
        
        Indoramin [D02.241.223.100.100.470]
        
        Metoclopramide [D02.241.223.100.100.510]
        
        Moclobemide [D02.241.223.100.100.600]
        
        Procainamide [D02.241.223.100.100.650]
        
        Procarbazine [D02.241.223.100.100.655]
        
        Raclopride [D02.241.223.100.100.761]
        
        Remoxipride [D02.241.223.100.100.796]
        
        Sulpiride [D02.241.223.100.100.866]
        
        Tiapride Hydrochloride [D02.241.223.100.100.933]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Benzoates [D02.455.426.559.389.127]
        
        Benzamides [D02.455.426.559.389.127.085]
        
        Acecainide [D02.455.426.559.389.127.085.033]
        
        Aminohippuric Acids [D02.455.426.559.389.127.085.067]
        
        Amisulpride [D02.455.426.559.389.127.085.084]
        
        Axitinib [D02.455.426.559.389.127.085.093]
        
        Bezafibrate [D02.455.426.559.389.127.085.101]
        
        Cisapride [D02.455.426.559.389.127.085.135]
        
        DEET [D02.455.426.559.389.127.085.230]
        
        Dinitolmide [D02.455.426.559.389.127.085.240]
        
        Hippurates [D02.455.426.559.389.127.085.460]
        
        Imatinib Mesylate [D02.455.426.559.389.127.085.465]
        
        Indoramin [D02.455.426.559.389.127.085.470]
        
        Metoclopramide [D02.455.426.559.389.127.085.510]
        
        Moclobemide [D02.455.426.559.389.127.085.600]
        
        Procainamide [D02.455.426.559.389.127.085.650]
        
        Procarbazine [D02.455.426.559.389.127.085.655]
        
        Raclopride [D02.455.426.559.389.127.085.761]
        
        Remoxipride [D02.455.426.559.389.127.085.796]
        
        Sulpiride [D02.455.426.559.389.127.085.866]
        
        Tiapride Hydrochloride [D02.455.426.559.389.127.085.933]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, 1-Ring [D03.383]
  - Azoles [D03.383.129]
    - Pyrazoles [D03.383.129.539]
      - Indazoles [D03.383.129.539.487]
        
        Axitinib [D03.383.129.539.487.065]
        
        Benzydamine [D03.383.129.539.487.130]
        
        Granisetron [D03.383.129.539.487.350]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indazoles [D03.633.100.449]

Axitinib Preferred

AG 013736 Narrower

Inlyta Narrower

Axitinib MeSH Descriptor Data 2024