Cytochrome P-450 CYP1B1 MeSH Descriptor Data 2024

MeSH Heading: Cytochrome P-450 CYP1B1
Tree Number(s): D08.244.453.005.500; D08.244.453.100.875; D08.811.682.690.708.170.010.500; D08.811.682.690.708.170.020.875; D12.776.422.220.453.010.500; D12.776.422.220.453.100.875
Unique ID: D065633
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D065633
Annotation: /antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS
Scope Note: A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
Entry Term(s): Cytochrome P450 CYP1B1; Cytochrome P450, Family 1, Subfamily B, Polypeptide 1; Cytochrome P4501B1
Registry Number: EC 1.14.14.1
Related Numbers: 156320-24-0
Public MeSH Note: 2015; CYTOCHROME P-450 CYPB1 was indexed under ARYL HYDROCARBON HYDROXYLASES 1995-2014
History Note: 2015
Date Established: 2015/01/01
Date of Entry: 2014/06/26
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Cytochromes [D08.244]
  - Cytochrome P-450 Enzyme System [D08.244.453]
    - Aryl Hydrocarbon Hydroxylases [D08.244.453.005]

Enzymes and Coenzymes [D08]
- Cytochromes [D08.244]
  - Cytochrome P-450 Enzyme System [D08.244.453]
    - Cytochrome P450 Family 1 [D08.244.453.100]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Oxygenases [D08.811.682.690]
      - Mixed Function Oxygenases [D08.811.682.690.708]
        
        Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
        
        Aryl Hydrocarbon Hydroxylases [D08.811.682.690.708.170.010]
        
        7-Alkoxycoumarin O-Dealkylase [D08.811.682.690.708.170.010.024]
        
        Aniline Hydroxylase [D08.811.682.690.708.170.010.050]
        
        Benzopyrene Hydroxylase [D08.811.682.690.708.170.010.110]
        
        Cytochrome P-450 CYP1A1 [D08.811.682.690.708.170.010.277]
        
        Cytochrome P-450 CYP1A2 [D08.811.682.690.708.170.010.443]
        
        Cytochrome P-450 CYP1B1 [D08.811.682.690.708.170.010.500]
        
        Cytochrome P-450 CYP2B1 [D08.811.682.690.708.170.010.550]
        
        Cytochrome P-450 CYP2B6 [D08.811.682.690.708.170.010.575]
        
        Cytochrome P-450 CYP2C8 [D08.811.682.690.708.170.010.590]
        
        Cytochrome P-450 CYP2D6 [D08.811.682.690.708.170.010.600]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Oxygenases [D08.811.682.690]
      - Mixed Function Oxygenases [D08.811.682.690.708]
        
        Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
        
        Cytochrome P450 Family 1 [D08.811.682.690.708.170.020]
        
        Cytochrome P-450 CYP1A1 [D08.811.682.690.708.170.020.500]
        
        Cytochrome P-450 CYP1A2 [D08.811.682.690.708.170.020.750]
        
        Cytochrome P-450 CYP1B1 [D08.811.682.690.708.170.020.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Hemeproteins [D12.776.422]
    - Cytochromes [D12.776.422.220]
      - Cytochrome P-450 Enzyme System [D12.776.422.220.453]
        
        Aryl Hydrocarbon Hydroxylases [D12.776.422.220.453.010]
        
        Aniline Hydroxylase [D12.776.422.220.453.010.050]
        
        Benzopyrene Hydroxylase [D12.776.422.220.453.010.110]
        
        Cytochrome P-450 CYP1A1 [D12.776.422.220.453.010.332]
        
        Cytochrome P-450 CYP1A2 [D12.776.422.220.453.010.443]
        
        Cytochrome P-450 CYP1B1 [D12.776.422.220.453.010.500]
        
        Cytochrome P-450 CYP2B1 [D12.776.422.220.453.010.550]
        
        Cytochrome P-450 CYP2B6 [D12.776.422.220.453.010.575]
        
        Cytochrome P-450 CYP2C8 [D12.776.422.220.453.010.590]
        
        Cytochrome P-450 CYP2D6 [D12.776.422.220.453.010.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Hemeproteins [D12.776.422]
    - Cytochromes [D12.776.422.220]
      - Cytochrome P-450 Enzyme System [D12.776.422.220.453]
        
        Cytochrome P450 Family 1 [D12.776.422.220.453.100]
        
        Cytochrome P-450 CYP1A1 [D12.776.422.220.453.100.500]
        
        Cytochrome P-450 CYP1A2 [D12.776.422.220.453.100.750]
        
        Cytochrome P-450 CYP1B1 [D12.776.422.220.453.100.875]

Cytochrome P-450 CYP1B1 Preferred

Concept UI: M0590251
Registry Number: EC 1.14.14.1
Related Numbers: 156320-24-0
Scope Note: A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
Terms: Cytochrome P-450 CYP1B1 Preferred Term
Term UI T853092
Date01/07/2014
LexicalTag ABX
ThesaurusID NLM (2015); Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
Term UI T853094
Date01/07/2014
LexicalTag NON
ThesaurusID NLM (2015); Cytochrome P4501B1
Term UI T853095
Date01/07/2014
LexicalTag ABX
ThesaurusID NLM (2015); Cytochrome P450 CYP1B1
Term UI T853093
Date01/07/2014
LexicalTag ABX
ThesaurusID NLM (2015)

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