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ecarin MeSH Supplementary Concept Data 2024


MeSH Supplementary
ecarin
Unique ID
C020097
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C020097
Entry Term(s)
Echis carinatus prothrombin-activating proteins
echarin
prothrombin activation fragments, ecarin
prothrombin activator (Echis carinatus venom)
Pharm Action
Fibrinolytic Agents
Registry Number
EC 3.4.24.-
Previous Indexing
*GLYCOPROTEINS (78-82)
*PROTHROMBIN (78-82)
PROTHROMBIN (76-82)
SNAKE VENOMS (76-79)
Heading Mapped to
*Endopeptidases
Frequency
125
Note
cleaves specifically Arg-Ile bond in prothrombin; procoagulant enzyme from Echis carinatus venom which converts prothrombin to thrombin
Source
J Biochem (Tokyo):83(2):559;1978
J Biol Chem 254(18):8751;1879
Thromb Res 15(1-2):143;1979
Thromb Res 15(1-2):27;1979
Thromb Res 7(4):611;1975
Indexing Information
Enzyme Activation
Viper Venoms
Date of Entry
1976/01/01
Revision Date
2012/07/10
ecarin Preferred
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