MeSH Browser

MeSH Heading: Hyaluronan Synthases
Tree Number(s): D08.811.913.400.450.480.500
Unique ID: D000076002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076002
Scope Note: Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
Entry Term(s): HAS1 Protein; HAS2 Protein; HAS3 Protein; Hyaluronan Synthase; Hyaluronan Synthase 1; Hyaluronan Synthase 2; Hyaluronan Synthase 3; Hyaluronan Synthetase; Hyaluronate Synthase; Hyaluronate Synthetase; Hyaluronic Acid Synthetase; hasA Enzyme
Registry Number: EC 2.4.1.212
Public MeSH Note: 2018; see HYALURONAN SYNTHASE 1976-2017; HYALURONAN SYNTHASES was indexed under GLUCURONOSYLTRANSFERASE 1976-2017
History Note: 2018 (1976); was HYALURONAN SYNTHASE 1976-2017
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000631759
Registry Number: EC 2.4.1.212
Scope Note: Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
Terms: Hyaluronan Synthases Preferred Term
Term UI T000924781
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (2018); Hyaluronan Synthase
Term UI T000924788
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (1976); Hyaluronic Acid Synthetase
Term UI T000924804
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (1976); Hyaluronate Synthetase
Term UI T000924803
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (1976); Hyaluronan Synthetase
Term UI T000924801
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (1976); Hyaluronate Synthase
Term UI T000924802
Date05/18/2017
LexicalTag NON
ThesaurusID NLM (1976)

Hyaluronan Synthases MeSH Descriptor Data 2024