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pimodivir MeSH Supplementary Concept Data 2025


MeSH Supplementary
pimodivir
Unique ID
C000605010
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000605010
Entry Term(s)
(2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo(2,3-b)pyridin-3-yl)-4-pyrimidinyl)amino)bicyclo(2.2.2)octane-2-carboxylic acid
Bicyclo(2.2.2)octane-2-carboxylic acid, 3-((5-fluoro-2-(5-fluoro-1H-pyrrolo(2,3-b)pyridin-3-yl)-4-pyrimidinyl)amino)-, (2S,3S)-
JNJ-63623872
VX-787
Registry Numbers
DFC121MXC3
Heading Mapped to
*Pyridines
*Pyrimidines
*Pyrroles
Frequency
13
Note
non‐nucleotide inhibitor of the polymerase basic protein 2 (PB2) subunit of the influenza A that is active against H1N1, H7N9 and H5N1, as well as influenza A strains with reduced susceptibility to NAIs
Source
Bioorg Med Chem Lett. 2015 May 1;25(9):1990-4
Date of Entry
2016/02/18
Revision Date
2019/11/12
pimodivir Preferred
VX-787 Narrower
JNJ-63623872 Narrower
(2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo(2,3-b)pyridin-3-yl)-4-pyrimidinyl)amino)bicyclo(2.2.2)octane-2-carboxylic acid Broader
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