MeSH Browser

MeSH Supplementary: PF-06263507
Unique ID: C000626590
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C000626590
Entry Term(s): anti-5T4 antibody-monomethylauristatin conjugate
Pharm Action: Antimitotic Agents
Antineoplastic Agents, Immunological
Registry Numbers: V7U0JSO7FH
Heading Mapped to: *Antigens, Neoplasm; *Oligopeptides; *Antibodies, Monoclonal, Humanized
Frequency: 1
Note: targets the cell-surface, tumor-associated antigen 5T4 and consists of a humanized IgG1 conjugated to the microtubule-disrupting agent monomethylauristatin-F by a non-cleavable maleimidocaproyl linker
Source: Invest New Drugs. 2017 Jun;35(3):315-323.
Date of Entry: 2018/03/21
Revision Date: 2019/10/30

PF-06263507 MeSH Supplementary Concept Data 2025