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tropifexor MeSH Supplementary Concept Data 2025


MeSH Supplementary
tropifexor
Unique ID
C000630573
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000630573
Entry Term(s)
2-((1R,5S)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)-1,2-oxazol-4-yl)methoxy)-8-azabicyclo(3.2.1)octan-8-yl)-4-fluoro-1,3-benzothiazole-6-carboxylic acid
LJN452
Registry Numbers
NMZ08KM76Z
0
Heading Mapped to
*Isoxazoles
*Benzothiazoles
Frequency
18
Note
novel and highly potent agonist of farnesoid X receptor (FXR)
Source
J Med Chem. 2017 Dec 28;60(24):9960-9973
Date of Entry
2019/04/02
Revision Date
2021/12/08
tropifexor Preferred
LJN452 Narrower
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