MeSH Browser

MeSH Supplementary: tomivosertib
Unique ID: C000630785
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C000630785
Entry Term(s): 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'-dione; eFT508; spiro(cyclohexane-1,3'(2'H)-imidazo(1,5-a)pyridine)-1',5'-dione, 6'-((6-amino-4-pyrimidinyl)amino)-8'-methyl-
Registry Numbers: U2H19X4WBV
Heading Mapped to: *Pyridines; *Pyrimidines
Frequency: 8
Note: a selective translation regulator and is part of a new class of cancer treatments known as immunotherapies that are designed to harness the body’s own immune system in fighting cancer. eFT508 is a highly potent and selective, oral inhibitor of MNK1 and MNK2 (MNK1/2).
Source: J Med Chem. 2018 Apr 26;61(8):3516-3540.
Date of Entry: 2019/04/26
Revision Date: 2019/04/26

tomivosertib MeSH Supplementary Concept Data 2025