MeSH Browser

MeSH Supplementary: celastrol methyl ester
Unique ID: C000718427
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C000718427
Entry Term(s): (9 beta,13 alpha,14 beta, 20 alpha)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid; 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid methyl ester; pristimerin
Registry Numbers: 28ZK7PR57S
Related Numbers: 1258-84-0
Heading Mapped to: *Pentacyclic Triterpenes
Frequency: 17
Note: isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME
Source: Nature. 1954 Jun 26;173(4417):1237-8.
Date of Entry: 2021/07/29
Revision Date: 2022/03/21

celastrol methyl ester MeSH Supplementary Concept Data 2025