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Simufilam MeSH Supplementary Concept Data 2025


MeSH Supplementary
Simufilam
Unique ID
C000719508
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000719508
Entry Term(s)
4-benzyl-8-methyl-1,4,8-triazaspiro(4.5)decan-3-one
PTI-125
Registry Numbers
6NV440YIO0
Heading Mapped to
*Spiro Compounds
Frequency
3
Note
oral small molecule drug candidate that binds and reverses an altered conformation of the scaffolding protein filamin A found in Alzheimer’s disease brain
Source
J Prev Alzheimers Dis . 2020;7(4):256-264.
Date of Entry
2021/10/05
Revision Date
2021/10/15
Simufilam Preferred
PTI-125 Narrower
4-benzyl-8-methyl-1,4,8-triazaspiro(4.5)decan-3-one Broader
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