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tapotoclax MeSH Supplementary Concept Data 2025


MeSH Supplementary
tapotoclax
Unique ID
C000720001
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000720001
Entry Term(s)
(3'R,4S,6'R,7'S,8'E,11'S,12'R)-7-chloro-7'-methoxy-11',12'-dimethyl-13',13'-dioxospiro(2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13lambda6-thia-1,14-diazatetracyclo(14.7.2.03,6.019,24)pentacosa-8,16(25),17,19(24)-tetraene)-15'-one
AMG-176
AMG176
Registry Numbers
97W7N9T08G
Heading Mapped to
*Naphthalenes
*Spiro Compounds
Frequency
1
Note
Mcl-1 Antagonist
Source
Clin Cancer Res . 2020 Jul 15;26(14):3856-3867.
Date of Entry
2021/11/09
Revision Date
2022/02/28
tapotoclax Preferred
AMG-176 Narrower
(3'R,4S,6'R,7'S,8'E,11'S,12'R)-7-chloro-7'-methoxy-11',12'-dimethyl-13',13'-dioxospiro(2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13lambda6-thia-1,14-diazatetracyclo(14.7.2.03,6.019,24)pentacosa-8,16(25),17,19(24)-tetraene)-15'-one Broader
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