MeSH Browser

MeSH Supplementary: mevastatin
Unique ID: C012258
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C012258
Entry Term(s): 6-demethylmevinolin; CS 500; ML 236B; ML-236B; ML236B; compactin
Pharm Action: Anti-Bacterial Agents
Anticholesteremic Agents
Antifungal Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number: 1UQM1K0W9X
Related Numbers: 60478-65-1; 73573-88-3
CAS Type 1 Name: 7-(1,2,6,7,8,8a-hexahydro-2-methyl-8- (2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide
Previous Indexing: *NAPHTHALENES (76-87)
Heading Mapped to: Lovastatin / *analogs & derivatives
Frequency: 460
Note: antifungal metabolite from Penicillium brevicopactum; potent inhibitory activity to sterol synthesis; structure
Source: Atherosclerosis 1980;35(3):259; Biochim Biophys Acta 1979;575(2):266; Biochim Biophys Acta 489(1):120;1977; Eur J Biochem 77:31;1977; Eur J Biochem 87(2):313;1978; J Antibiotics 29(12):1346;1976; J Biol Chem 1980;255(8):3715; J Biol Chem 253(4):1121;1978; J Chem Soc Perkin I 11:1165;1976; Jpn J Med Sci Biol 31(3):225;1978; Lancet 2(8104/5):1342;1978; Proc Natl Acad Sci USA 1979;76(11):5709
Date of Entry: 1976/01/01
Revision Date: 2012/11/05

mevastatin MeSH Supplementary Concept Data 2023