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mevastatin
MeSH Supplementary Concept Data 2023
Details
Concepts
MeSH Supplementary
mevastatin
Unique ID
C012258
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C012258
Entry Term(s)
6-demethylmevinolin
CS 500
ML 236B
ML-236B
ML236B
compactin
Pharm Action
Anti-Bacterial Agents
Anticholesteremic Agents
Antifungal Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number
1UQM1K0W9X
Related Numbers
60478-65-1
73573-88-3
CAS Type 1 Name
7-(1,2,6,7,8,8a-hexahydro-2-methyl-8- (2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide
Previous Indexing
*NAPHTHALENES (76-87)
Heading Mapped to
Lovastatin
/
*analogs & derivatives
Frequency
460
Note
antifungal metabolite from Penicillium brevicopactum; potent inhibitory activity to sterol synthesis; structure
Source
Atherosclerosis 1980;35(3):259
Biochim Biophys Acta 1979;575(2):266
Biochim Biophys Acta 489(1):120;1977
Eur J Biochem 77:31;1977
Eur J Biochem 87(2):313;1978
J Antibiotics 29(12):1346;1976
J Biol Chem 1980;255(8):3715
J Biol Chem 253(4):1121;1978
J Chem Soc Perkin I 11:1165;1976
Jpn J Med Sci Biol 31(3):225;1978
Lancet 2(8104/5):1342;1978
Proc Natl Acad Sci USA 1979;76(11):5709
Date of Entry
1976/01/01
Revision Date
2012/11/05
Expand All
Collapse All
mevastatin
Preferred
Concept UI
M0059179
Registry Number
1UQM1K0W9X
Related Numbers
60478-65-1
73573-88-3
Terms
mevastatin
Preferred Term
Term UI
T089181
LexicalTag
NON
ThesaurusID
compactin
Term UI
T089182
LexicalTag
NON
ThesaurusID
NLM (1976)
6-demethylmevinolin
Term UI
T089177
LexicalTag
NON
ThesaurusID
NLM (1976)
CS 500
Narrower
Concept UI
M0059175
Terms
CS 500
Preferred Term
Term UI
T089178
LexicalTag
LAB
ThesaurusID
NLM (1976)
ML 236B
Narrower
Concept UI
M0059176
Terms
ML 236B
Preferred Term
Term UI
T089179
LexicalTag
LAB
ThesaurusID
NLM (1976)
ML236B
Term UI
T419687
Date
07/24/2000
LexicalTag
LAB
ThesaurusID
NLM (2000)
ML-236B
Term UI
T089180
LexicalTag
LAB
ThesaurusID
NLM (1976)
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