NLM Logo

mevastatin MeSH Supplementary Concept Data 2024


MeSH Supplementary
mevastatin
Unique ID
C012258
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C012258
Entry Term(s)
6-demethylmevinolin
CS 500
ML 236B
ML-236B
ML236B
compactin
Pharm Action
Anti-Bacterial Agents
Anticholesteremic Agents
Antifungal Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Related Numbers
60478-65-1
73573-88-3
CAS Type 1 Name
7-(1,2,6,7,8,8a-hexahydro-2-methyl-8- (2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide
Previous Indexing
*NAPHTHALENES (76-87)
Heading Mapped to
Lovastatin / analogs & derivatives
Frequency
460
Note
antifungal metabolite from Penicillium brevicopactum; potent inhibitory activity to sterol synthesis; structure
Source
Atherosclerosis 1980;35(3):259
Biochim Biophys Acta 1979;575(2):266
Biochim Biophys Acta 489(1):120;1977
Eur J Biochem 77:31;1977
Eur J Biochem 87(2):313;1978
J Antibiotics 29(12):1346;1976
J Biol Chem 1980;255(8):3715
J Biol Chem 253(4):1121;1978
J Chem Soc Perkin I 11:1165;1976
Jpn J Med Sci Biol 31(3):225;1978
Lancet 2(8104/5):1342;1978
Proc Natl Acad Sci USA 1979;76(11):5709
Date of Entry
1976/01/01
Revision Date
2012/11/05
mevastatin Preferred
CS 500 Narrower
ML 236B Narrower
page delivered in 0.005s