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alpha-sarcin MeSH Supplementary Concept Data 2025


MeSH Supplementary
alpha-sarcin
Unique ID
C014801
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C014801
Pharm Action
Protein Synthesis Inhibitors
Registry Numbers
1407-48-3
CAS Type 1 Name
1407-48-3
Previous Indexing
*FUNGAL PROTEINS (77-97)
Heading Mapped to
*Endoribonucleases
*Fungal Proteins
Frequency
219
Note
basic protein 150 aa, MW 16 kDa; isolated from aspergillus giganteus; sequence similarity with ribonucleases such as RIBONUCLEASE T1; 85% identity with restrictocin; a ribotoxin cleaving the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of rat 28S RIBOSOMAL RNA; sometimes called a ribosome-inactivating protein but falls outside the normal definition of plant RIP that de-adenylate rRNA
Source
Biochem J 170:57;1978
Nucleic Acids Res 4(4):1097;1977
Date of Entry
1977/01/01
Revision Date
2004/08/06
alpha-sarcin Preferred
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