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((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol MeSH Supplementary Concept Data 2024


MeSH Supplementary
((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol
Unique ID
C018658
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C018658
Entry Term(s)
((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol, (E)-isomer
(E)-((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol
DMEA-MIEP
Registry Number
72825-08-2
Related Numbers
79798-38-2
CAS Type 1 Name
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-
Heading Mapped to
*Propanolamines
Frequency
1
Note
16X more potent than labetalol in beta-adrenergic receptor blockade & lowered blood pressure in spontaneously hypertensive rats; structure given in first source
Source
J Med Chem 1981;24(12):1460
Date of Entry
1982/01/26
Revision Date
2000/08/22
((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol Preferred
((1,1-dimethylethyl)amino)-3-(2-(2-(3-methyl-5-isoxazolyl)ethenyl)phenoxy)-2-propanol, (E)-isomer Narrower
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