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(T,G)-A-L MeSH Supplementary Concept Data 2024


MeSH Supplementary
(T,G)-A-L
Unique ID
C021759
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C021759
Entry Term(s)
(L-tyrosine-L-glutamic acid)-poly(DL-alanine)-poly(L-lysine)
(Tyr-Tyr-Glu-Glu)-poly(DL-Ala)-poly(Lys)
Cop 1 (polymer)
GLAT copolymer
TGAL copolymer
copolymer I (synthetic peptide)
multideterminant antigen (T,G)-A-L
poly-L-(Tyr,Glu)-poly-DL-Ala-poly-L-Lys
synthetic peptide copolymer I
Pharm Action
Immunosuppressive Agents
Registry Number
28704-27-0
CAS Type 1 Name
L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine
Heading Mapped to
*Peptides
Frequency
139
Note
synthetic polypeptide consisting of alanine, glutamic acid, lysine & tyrosine; nonencephalitogenic & nontoxic; capable of suppressing experimental allergic encehalomyelitis; improvement noted in patients with multiple sclerosis; antigen-specific helper factor
Source
Ann Neurol 1982;11(3):317
Eur J Immunol 9(7):501;1979
Eur J Immunol 9(7):553;1979
J Exp Med 1980;151(2):265
Transplant Proc 1979;11(4):1860
Indexing Information
T-Lymphocytes, Helper-Inducer
Date of Entry
1980/01/01
Revision Date
2002/10/23
(T,G)-A-L Preferred
(Tyr-Tyr-Glu-Glu)-poly(DL-Ala)-poly(Lys) Narrower
TGAL copolymer Narrower
GLAT copolymer Narrower
multideterminant antigen (T,G)-A-L Narrower
poly-L-(Tyr,Glu)-poly-DL-Ala-poly-L-Lys Narrower
(L-tyrosine-L-glutamic acid)-poly(DL-alanine)-poly(L-lysine) Narrower
copolymer I (synthetic peptide) Narrower
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