MeSH Browser

MeSH Supplementary: phosphoribosylformylglycinamidine synthetase
Unique ID: C022385
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C022385
Entry Term(s): 5'-phosphoribosyl-N-formylglycinamide amidotransferase; FGAM synthase; FGAM synthase I; FGAM synthase II; FGAM synthetase; FGAR amidotransferase; FGAR synthetase; PFAS protein; PFAS protein, human; formylglycineamide ribonucleotide amidotransferase
Registry Numbers: EC 6.3.5.3
Related Numbers: 9032-84-2
CAS Type 1 Name: 2-formamido-N-ribosylacetamide 5'-phosphate L-glutamine amido-ligase (adenosine diphosphate)
Previous Indexing: GLUTAMINE (74-80); GLYCINE/analogs (74-82); *LIGASES (74-97); RIBONUCLEOTIDES (74-82); RIBOSEMONOPHOSPHATES (74-80)
Heading Mapped to: *Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor
Frequency: 64
Note: involved in purine nucleotide biosynthesis; FGAM synthase I contains the glutamine amide transfer domain and FGAM synthase II contains the aminator domain of FGAM synthase
Source: Biochem 16(6):1065;1977; Biochem Genet 12(5):393;1974; J Cell Physiol 101(2):293;1979; Methods Enzymol 51:193;1978
Date of Entry: 1974/01/01
Revision Date: 2023/09/18

phosphoribosylformylglycinamidine synthetase MeSH Supplementary Concept Data 2025