MeSH Browser

MeSH Supplementary: E 64
Unique ID: C024974
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C024974
Entry Term(s): E-64; L-trans-epoxysuccinyl-leucylamido(4-guanidino)butane; N-(N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl)agmatine
Pharm Action: Antimalarials
Cysteine Proteinase Inhibitors
Registry Numbers: R76F7856MV
Related Numbers: 66701-25-5
CAS Type 1 Name: Oxiranecarboxylic acid, 3-(((1-(((4-((aminoiminomethyl)amino)butyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
Previous Indexing: *AGMATINE/analogs (80-82)
Heading Mapped to: Leucine / analogs & derivatives
Frequency: 420
Note: cysteine protease inhibitor of microbial origin, which inhibits cathepsin B (EC 3.4.22.1) and cathepsin L (EC 3.4.22.-)
Source: Biochem Biophys Res Commun 1980;93(3):713
Indexing Information: Cathepsins
Date of Entry: 1980/07/09
Revision Date: 2015/11/20

E 64 MeSH Supplementary Concept Data 2025