MeSH Browser

MeSH Supplementary: diacerein
Unique ID: C025292
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C025292
Entry Term(s): 1,8-diacetoxy-3-carboxyanthraquinone; 2-anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-; 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid; 4,5-diacetoxyanthraquinone-2-carboxylic acid; 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid, diacetate; AC-201; AC-203; Artrodar; Diora; Fisiodar; M-01AX21; M01AX21; SF-277; SF277; Verboril; Zondar; diacerhein; diacetyl-rhein; diacetylrhein; rhein diacetate
Pharm Action: Anti-Inflammatory Agents
Registry Number: 4HU6J11EL5
Related Numbers: 13739-02-1
Heading Mapped to: *Anthraquinones
Frequency: 296
Note: chelates with bivalent metals; a quinone which possesses redox properties; metabolized to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases; called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase;
Source: Curr Med Res Opin 1980;6(8):548
Date of Entry: 1980/08/15
Revision Date: 2022/03/30

diacerein MeSH Supplementary Concept Data 2024