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meteneprost MeSH Supplementary Concept Data 2024


MeSH Supplementary
meteneprost
Unique ID
C025505
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C025505
Entry Term(s)
9-deoxo-16,16-dimethyl-9-methylene-PGE2
9-deoxo-16,16-dimethyl-9-methyleneprostaglandin E2
9-deoxy-16,16-dimethyl-9-methylene-PGF2
9-methylene-16,16-dimethyl PGE2
9-methylene-PGE2
Pharm Action
Abortifacient Agents, Nonsteroidal
Registry Number
269EB4R1TV
Related Numbers
61263-35-2
CAS Type 1 Name
prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene, (5Z,11 alpha,13E,15R)-
Heading Mapped to
16,16-Dimethylprostaglandin E2 / *analogs & derivatives
Frequency
46
Note
9-deoxo-9-methylene-PGEs are possible solution to PGE stability problem; stable in aqueous media from pH 1 to 14 & have biological properties similar to corresponding PGEs; cpd tested for use as early pregnancy terminater & has low incidence of nausea & gastrointestinal side effects; note that cpd is derivative of both PGE2 & PGF2alpha; structure in first source
Source
Adv Prostaglandin Thromboxane Res 1980;6:355
Date of Entry
1980/07/18
Revision Date
2012/11/05
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