MeSH Browser

MeSH Supplementary: anthrax toxin
Unique ID: C030325
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C030325
Entry Term(s): 63 kDa anthrax protective antigen, Bacillus anthracis; 83 kDa anthrax protective antigen, Bacillus anthracis; Bacillus anthracis calmodulin-dependent adenylate cyclase; Bacillus anthracis, protective antigen; LF protein, Bacillus anthracis; LeTx toxin, B anthracis; PA antigen, Bacillus anthracis; PA63 protective antigen, Bacillus anthracis; PA63 protein, Bacillus anthracis; PA83 protective antigen, Bacillus anthracis; anthrax edema factor; anthrax lethal factor; anthrax protective antigen; anthrax toxin EF; anthrax toxin LF; anthrax toxin PA; anthrax toxins translocating protein, Bacillus anthracis; cya protein, Bacillus anthracis; edema factor exotoxin; edema factor, Bacillus anthracis; edema factor, anthrax toxin; edema toxin, Bacillus anthracis; lef protein, Bacillus anthracis; lethal factor, anthrax; lethal toxin, Bacillus anthracis; pag protein, Bacillus anthracis; pagA protein, Bacillus anthracis; protective antigen, anthrax
Registry Numbers: 0; EC 4.6.1.1; EC 3.4.24.83; OSR4FXO1IU
Related Numbers: EC 3.4.24.83; EC 4.6.1.1; OSR4FXO1IU
Heading Mapped to: *Antigens, Bacterial; *Bacterial Toxins
Frequency: 1756
Note: consists of 3 separate proteins: PA (protective antigen/factor), EF (edema factor) & LF (lethal factor); these three are nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells; Bacillus anthracis calmodulin-dependent adenylate cyclase is component of EF protein, is a zinc-dependent metalloprotease; PA63 is a proteolytic fragment of PA83
Source: Pharmacol Ther 1981;12(3):501
Indexing Information: Adenylyl Cyclases; Metalloendopeptidases; Anthrax Vaccines
Date of Entry: 1981/07/10
Revision Date: 2018/11/16

anthrax toxin Preferred

anthrax edema factor Narrower

anthrax lethal factor Narrower

Concept UI: M0096006
Registry Numbers: EC 3.4.24.83
Terms: anthrax lethal factor Preferred Term
Term UI T434067
Date01/25/2001
LexicalTag NON
ThesaurusID NLM (2001); LF protein, Bacillus anthracis
Term UI T522400
Date10/14/2002
LexicalTag NON
ThesaurusID NLM (2002); anthrax toxin LF
Term UI T126010
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1981); LeTx toxin, B anthracis
Term UI T607732
Date09/02/2004
LexicalTag NON
ThesaurusID NLM (2004); lethal factor, anthrax
Term UI T611436
Date09/29/2004
LexicalTag NON
ThesaurusID NLM (2004); lef protein, Bacillus anthracis
Term UI T611437
Date09/29/2004
LexicalTag NON
ThesaurusID NLM (2004); lethal toxin, Bacillus anthracis
Term UI T524339
Date10/26/2002
LexicalTag NON
ThesaurusID NLM (2002)

PA83 protective antigen, Bacillus anthracis Narrower

PA63 protective antigen, Bacillus anthracis Narrower

anthrax protective antigen Narrower

anthrax toxin MeSH Supplementary Concept Data 2025