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dihydromevinolin MeSH Supplementary Concept Data 2024


MeSH Supplementary
dihydromevinolin
Unique ID
C031351
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C031351
Entry Term(s)
4a,5-dihydromevinolin
Pharm Action
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number
77517-29-4
CAS Type 1 Name
Butanoic acid, 2-methyl-, 1,2,3,4,4a,7,8,8a-octahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,4aalpha,7beta,8beta(2S*,4S*),8abeta))-
Previous Indexing
*NAPHTHALENES (81-87)
Heading Mapped to
Lovastatin / *analogs & derivatives
Frequency
2
Note
potent hypocholesterolemic agent from Aspergillus terreus; inhibits HMG-CoA reductase; RN given refers to (1S-(1alpha(R*),3alpha,4aalpha,7beta,8beta(2S*,4S*),8abeta))-isomer; structure in first source
Source
J Antibiot (Tokyo) 1981;34(5):507
Date of Entry
1981/09/23
Revision Date
2015/08/18
dihydromevinolin Preferred
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