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dihydrocompactin MeSH Supplementary Concept Data 2024


MeSH Supplementary
dihydrocompactin
Unique ID
C031380
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C031380
Entry Term(s)
4a,5-dihydrocompactin
Pharm Action
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number
78366-44-6
CAS Type 1 Name
Butanoic acid, 2-methyl-, 1,2,3,4,4a,7,8,8a-octahydro-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),4aalpha,7beta,8beta(2S*,4S*),8abeta))-
Previous Indexing
*NAPHTHALENES (81-87)
Heading Mapped to
Lovastatin / *analogs & derivatives
Frequency
2
Note
antibiotic from Penicillium citrinum which is potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (EC 1.1.1.34); structure in first source
Source
J Antibiot (Tokyo) 1981;34(5):614
Date of Entry
1981/10/14
Revision Date
2015/08/18
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