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tyrocidine synthetase MeSH Supplementary Concept Data 2025


MeSH Supplementary
tyrocidine synthetase
Unique ID
C035180
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C035180
Entry Term(s)
tycA protein, Brevibacillus parabrevis
tycB protein, Brevibacillus parabrevis
tycC protein, Brevibacillus parabrevis
tyrocidine synthetase II, Brevibacillus parabrevis
tyrocidine synthetase III, Brevibacillus parabrevis
Registry Numbers
EC 6.3.2.-
EC 6.3.2.-
Heading Mapped to
*Peptide Synthases
Frequency
60
Note
consists of 3 multifunctional enzymes involved in the biosynthesis of the cyclic decapeptide tyrocidine; tyrocidine synthetase 1 activates the phenylalanine & racemizes it; tyrocidine sythetase 2 activates proline, phenylalanine & phenylalanine in positions 2,3 & 4 & racemizes phenylalanine at position 4; tyrocidine synthetase 3 catalyzes the activation of the remaining 6 amino acids; see also record for tyrocidine synthetase 1; GenBank AF004835 (tycB and tycC)
Source
J Bacteriol 1982;151(2):580
Date of Entry
1982/09/08
Revision Date
2004/09/01
tyrocidine synthetase Preferred
tycB protein, Brevibacillus parabrevis Narrower
tycC protein, Brevibacillus parabrevis Narrower
tycA protein, Brevibacillus parabrevis Narrower
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