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fosinoprilat MeSH Supplementary Concept Data 2024


MeSH Supplementary
fosinoprilat
Unique ID
C046965
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C046965
Entry Term(s)
SQ 27519
SQ-27,519
SQ-27519
fosfenopril
fosinoprilic acid
Pharm Action
Angiotensin-Converting Enzyme Inhibitors
Anti-Arrhythmia Agents
Antihypertensive Agents
Registry Number
S312EY6ZT8
Related Numbers
95399-71-6
CAS Type 1 Name
L-Proline, 4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-, trans-
Previous Indexing
*ORGANOPHOSPHORUS COMPOUNDS (85-92)
PROLINE/*analogs (85-92)
Heading Mapped to
Fosinopril / *analogs & derivatives
Frequency
30
Note
active phosphinic acid metabolite of prodrug fosenopril, which is activated by esterases in vivo; structure given in first source; binds zinc with phosphinic acid group
Source
Anal Biochem 1985;148(2):401
Indexing Information
Prodrugs
Date of Entry
1985/05/16
Revision Date
2012/11/05
fosinoprilat Preferred
fosfenopril Related
SQ 27519 Narrower
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