MeSH Browser

MeSH Supplementary: proinsulin endopeptidase I
Unique ID: C054196
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C054196
Entry Term(s): Ca-dependent endopeptidase I; calcium-dependent acidic endopeptidase I
Registry Numbers: EC 3.4.99.-
Heading Mapped to: *Endopeptidases
Frequency: 10
Note: involved in proteolytic conversion of proinsulin into insulin; pH optimum 5.5; cleaves exclusively on the C-terminal side of Arg 31.Arg 32 (B-chain/C-peptide junction); not inhibited by inhibitors of aspartic proteinases
Source: Biochem J 1987;246(2):279
Date of Entry: 1987/12/28
Revision Date: 2001/04/24

proinsulin endopeptidase I MeSH Supplementary Concept Data 2025