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fibrolase MeSH Supplementary Concept Data 2025


MeSH Supplementary
fibrolase
Unique ID
C058789
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C058789
Entry Term(s)
Agkistrodon contortrix fibrin-degrading metalloprotease
Registry Numbers
EC 3.4.24.-
Heading Mapped to
*Metalloendopeptidases
Frequency
34
Note
from the venom of Agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; MW 23-25kDa; cleaves primarily the Aa-chain of human fibrinogen & fibrin between the Lys-413 & Leu-414 position; the Bb chain is cleaved more slowly; gamma chain is minimally affected
Source
Thromb Res 1988;52(6):541
Date of Entry
1989/04/18
Revision Date
2001/05/22
fibrolase Preferred
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