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U 81749 MeSH Supplementary Concept Data 2024


MeSH Supplementary
U 81749
Unique ID
C062520
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C062520
Entry Term(s)
Tba-Cha(psi)(CH(OH)CH2)Val-Ile-Amp
U-81749
tert-butylacetyl-cyclohexylalanine-hydroxyethylene isostere-valyl-isoleucyl-aminomethylpyridine
Registry Number
126103-94-4
CAS Type 1 Name
Cyclohexanehexanamide, delta-((3,3-dimethyl-1-oxobutyl)amino)-gamma-hydroxy-alpha-(1-methylethyl)-N-(2-methyl-1-(((2-pyridinylmethyl)amino)carbonyl)butyl)-, (alphaS-(N(1R*,2R*),alphaR*,gammaR*,deltaR*))-
Heading Mapped to
*Oligopeptides
Frequency
4
Note
structure given in first source; synthetic HIV-1 protease inhibitor with antiviral activity; arrests HIV-like particle maturation
Source
Science 1990;247(4941):454
Date of Entry
1990/02/22
Revision Date
2002/01/16
U 81749 Preferred
tert-butylacetyl-cyclohexylalanine-hydroxyethylene isostere-valyl-isoleucyl-aminomethylpyridine Broader
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