MeSH Browser

MeSH Supplementary: dolastatin 10
Unique ID: C064570
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C064570
Entry Term(s): Deo-Dola 10; NSC 376128; deo-dolastatin 10; isodolastatin 10
Pharm Action: Antineoplastic Agents
Tubulin Modulators
Registry Number: EI946JT51X
Related Numbers: 110417-88-4
CAS Type 1 Name: L-valinamide, N,N-dimethyl-L-valyl-N-((1S,2R)-2-methoxy-4-((2S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((1S)-2-phenyl-1-(2-thiazolyl)ethyl)amino)propyl)-1-pyrrolidinyl)-1-((1S)-1-methylpropyl)-4-oxobutyl)-N-methyl-
Previous Indexing: *OLIGOPEPTIDES (1990-2008)
Heading Mapped to: *Depsipeptides
Frequency: 110
Note: from mollusk Dolabella auricularia; contains four amino acids, dolavaline, dolaisoleucine, dolaproine, valine and the primary amine dolaphenine; deo-dolastatin 10 is a new dolastatin 10 chiral derivative with MW of 784
Source: Biochem Pharmacol 1990;39(12):1941
Date of Entry: 1990/07/18
Revision Date: 2017/06/28

dolastatin 10 MeSH Supplementary Concept Data 2024