MeSH Browser

MeSH Supplementary: A 65281
Unique ID: C074586
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C074586
Entry Term(s): A-65281
Registry Number: 111279-49-3
CAS Type 1 Name: Isothiazolo(5,4-b)quinoline-3,4(2H,9H)-dione, 9-cyclopropyl-6,8-difluoro-7-(1-piperazinyl)-
Heading Mapped to: *Fluoroquinolones
Frequency: 1
Note: potent inhibitor of the P4-unknotting reaction & inducer of DNA breakage catalyzed by topoisomerase II; an anti-infective agent, fluoroquinolone; structure given in first source
Source: Antimicrob Agents Chemother 1992 Jan;36(1):81-6
Date of Entry: 1992/06/17
Revision Date: 2003/08/08

A 65281 MeSH Supplementary Concept Data 2024