NLM Logo

troxacitabine MeSH Supplementary Concept Data 2022


MeSH Supplementary
troxacitabine
Unique ID
C074908
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C074908
Entry Term(s)
(2S-cis)-4-amino-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)-2(1H)-pyrimidinone
1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine
2R(-)-cis-HMD-cytosine
2R(-)-trans-HMD-cytosine
2S(-)-cis-HMD-cytosine
BCH 4556
BCH-4556
HMD-cytosine
Troxatyl
beta-L-dioxolane-cytidine
troxacitabine, 2R(-)-cis-isomer
troxacitabine, 2R(-)-trans-isomer
troxacitabine, 2S(-)-trans-isomer
troxacitabine, cis-(+-)-isomer
troxacitabine, trans-(+-)-isomer
Pharm Action
Antineoplastic Agents
Anti-HIV Agents
Registry Number
60KQZ0388Y
Related Numbers
141196-84-1
145416-37-1
145511-98-4
145918-75-8
151282-98-3
Heading Mapped to
Cytosine / *analogs & derivatives
*Dioxolanes
Frequency
70
Note
shows good anti-HIV activity without cytotoxicity
Source
J Med Chem 1992 May 29;35(11):1987-95
Date of Entry
1992/07/06
Revision Date
2020/11/30
troxacitabine Preferred
troxacitabine, 2R(-)-cis-isomer Narrower
Troxatyl Narrower
troxacitabine, 2S(-)-trans-isomer Narrower
troxacitabine, cis-(+-)-isomer Narrower
troxacitabine, trans-(+-)-isomer Narrower
BCH 4556 Narrower
troxacitabine, 2R(-)-trans-isomer Narrower
page delivered in 0.004s