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6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
MeSH Supplementary Concept Data 2024
Details
Concepts
MeSH Supplementary
6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Unique ID
C074923
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C074923
Entry Term(s)
(+)(-)-FEMEPPEP
(+)-FEMEPPEP
6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
FEMEPPEP
Registry Number
141117-01-3
Related Numbers
141116-96-3
Heading Mapped to
*Pyrazoles
*Pyridines
Frequency
1
Note
structure given in first source; more potent than lovastatin in inhibiting cholesterol biosynthesis; RN refers to the (+)-isomer
Source
J Med Chem 1992 May 29;35(11):2095-2103
Date of Entry
1992/07/06
Revision Date
2001/07/17
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6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Preferred
Concept UI
M0202088
Registry Number
141117-01-3
Related Numbers
141116-96-3
Terms
6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Preferred Term
Term UI
T232093
LexicalTag
NON
ThesaurusID
NLM (1992)
FEMEPPEP
Term UI
T232092
LexicalTag
NON
ThesaurusID
NLM (1992)
(+)-FEMEPPEP
Narrower
Concept UI
M0202086
Terms
(+)-FEMEPPEP
Preferred Term
Term UI
T232091
LexicalTag
NON
ThesaurusID
NLM (1992)
6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
Narrower
Concept UI
M0325754
Registry Number
141116-96-3
Terms
6-(2-(5-(4-fluorophenyl)-3-(1-methylethyl)-1-(2-pyridinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
Preferred Term
Term UI
T355754
Date
08/18/1999
LexicalTag
NON
ThesaurusID
NLM (1992)
(+)(-)-FEMEPPEP
Term UI
T232090
LexicalTag
NON
ThesaurusID
NLM (1992)
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