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6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
MeSH Supplementary Concept Data 2024
Details
Concepts
MeSH Supplementary
6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Unique ID
C074924
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C074924
Entry Term(s)
(+)(-)-PHEMEPPEP
(+)-PHEMEPPEP
6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
PHEMEPPEP
Registry Number
141117-03-5
Related Numbers
141046-33-5
Previous Indexing
*LACTONES (92)
Heading Mapped to
*Pyrazines
*Pyrazoles
Frequency
1
Note
structure given in first source; more potent than lovastatin in inhibiting cholesterol biosynthesis; RN refers to the (+)-isomer
Source
J Med Chem 1992 May 29;35(11):2095-2103
Date of Entry
1992/07/06
Revision Date
2001/07/17
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6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Preferred
Concept UI
M0202092
Registry Number
141117-03-5
Related Numbers
141046-33-5
Terms
6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one
Preferred Term
Term UI
T232097
LexicalTag
NON
ThesaurusID
NLM (1992)
PHEMEPPEP
Term UI
T232096
LexicalTag
NON
ThesaurusID
NLM (1992)
(+)-PHEMEPPEP
Narrower
Concept UI
M0202090
Terms
(+)-PHEMEPPEP
Preferred Term
Term UI
T232095
LexicalTag
NON
ThesaurusID
NLM (1992)
6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
Narrower
Concept UI
M0325755
Registry Number
141046-33-5
Terms
6-(2-(5-(p-fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl)ethenyl)tetrahydro-4-hydroxy-2H-pyran-2-one, (+)(-)-isomer
Preferred Term
Term UI
T355755
Date
08/18/1999
LexicalTag
NON
ThesaurusID
NLM (1992)
(+)(-)-PHEMEPPEP
Term UI
T232094
LexicalTag
NON
ThesaurusID
NLM (1992)
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