MeSH Browser

MeSH Supplementary: scaffold protein, Herpes simplex virus-1
Unique ID: C079287
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C079287
Entry Term(s): HSV-1 ICP35 protease; HSV-1 capsid protein VP24; Herpes simplex virus-1 ICP35 proteinase; ICP35 protease, HSV-1; ICP35 protease, Herpes simplex virus-1; ICP35 protease, Human herpesvirus 1; UL26 protein, HSV-1; UL26 protein, Herpes simplex virus-1; UL26 protein, Human herpesvirus 1; UL26.5 protein, Herpes simplex virus-1; VP24 protein, Herpes simplex virus-1; herpes simplex virus type 1 capsid VP24; internal scaffold protein, Herpes simplex virus-1; scaffold protein, Human herpesvirus 1
Registry Numbers: 0; EC 3.4.21.-
Previous Indexing: *CAPSID (1992-2003); *PEPTIDE PEPTIDOHYDROLASES (93); *SERINE ENDOPEPTIDASES (1992-2003)
Heading Mapped to: *Viral Proteins
Frequency: 56
Note: encoded by overlapping in-frame UL26 and UL26.5 transcripts; essential for formation and efficient maturation of capsids; N-terminal protease domain, and its C-terminal oligomerization and capsid protein-binding domains are identical to those of UL26.5. The UL26 protease cleaves itself, releasing minor scaffold proteins VP24 and VP21protease cleavage produces two polypeptides, Prn and ICP35a; do not confuse with HSV-1 assembly protein ICP35
Source: J Gen Virol 1992 Oct;73(Pt 10):2709-13
Indexing Information: Capsid; Serine Endopeptidases
Date of Entry: 1992/11/17
Revision Date: 2004/02/09

scaffold protein, Herpes simplex virus-1 MeSH Supplementary Concept Data 2025