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4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol MeSH Supplementary Concept Data 2024


MeSH Supplementary
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol
Unique ID
C081017
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C081017
Entry Term(s)
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, (cis)-isomer
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, cis-(+)-isomer
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, cis-(-)-isomer
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, trans-(+-)-isomer
SSF 109
SSF-109
Registry Number
129586-32-9
Related Numbers
100199-27-7
133883-01-9
133883-02-0
133883-04-2
Heading Mapped to
*Triazoles
Frequency
2
Note
sterol biosynthesis inhibitor; inhibits the conversion of lanosterol to desmosterol & dihydrolanosterol to cholesterol indicating that the site of action is the inhibition of the 14 alpha-methyl demethylase activity; RN given refers to the cis-(+-)-isomer; RN for cpd without isomeric designation is not avail 5/93
Source
Steroid 1993 Feb;58(2):74-8
Date of Entry
1993/05/31
Revision Date
2001/12/07
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol Preferred
SSF 109 Narrower
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, cis-(-)-isomer Narrower
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, trans-(+-)-isomer Narrower
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, (cis)-isomer Narrower
4-chlorophenyl-2-(1H-1,2,4-triazol-yl)cycloheptanol, cis-(+)-isomer Narrower
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