MeSH Browser

MeSH Supplementary: transforming growth factor(alpha)-Pseudomonas exotoxin A (35)
Unique ID: C081440
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C081440
Entry Term(s): PE35-TGFalpha; PE35-TGFalpha-KDEL; TGFalpha-PE35
Registry Numbers: 0
Previous Indexing: *Exotoxin A (1996-2024)
Heading Mapped to: Recombinant Fusion Proteins; *Transforming Growth Factor alpha; *Pseudomonas aeruginosa Exotoxin A
Frequency: 2
Note: a recombinant form of Pseudomonas exotoxin A containing TGFalpha near its carboxyl terminus for the treatment of bladder cancer; contains a modified carboxyl-terminal sequence KDEL which increases the toxin activity by 10 to 700 fold more potent than TP40 (TGFalpha-PE40)
Source: J Urol 1993 Jun;149(6):1626-32
Date of Entry: 1993/06/28
Revision Date: 2023/08/09

Concept UI: M0217225
Registry Numbers: 0
Terms: transforming growth factor(alpha)-Pseudomonas exotoxin A (35) Preferred Term
Term UI T247230
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1993); TGFalpha-PE35
Term UI T247229
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1993); PE35-TGFalpha-KDEL
Term UI T247228
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1993); PE35-TGFalpha
Term UI T247227
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1993)

transforming growth factor(alpha)-Pseudomonas exotoxin A (35) MeSH Supplementary Concept Data 2025