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transforming growth factor(alpha)-Pseudomonas exotoxin A (35) MeSH Supplementary Concept Data 2025


MeSH Supplementary
transforming growth factor(alpha)-Pseudomonas exotoxin A (35)
Unique ID
C081440
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C081440
Entry Term(s)
PE35-TGFalpha
PE35-TGFalpha-KDEL
TGFalpha-PE35
Registry Numbers
0
Previous Indexing
*Exotoxin A (1996-2024)
Heading Mapped to
Recombinant Fusion Proteins
*Transforming Growth Factor alpha
*Pseudomonas aeruginosa Exotoxin A
Frequency
2
Note
a recombinant form of Pseudomonas exotoxin A containing TGFalpha near its carboxyl terminus for the treatment of bladder cancer; contains a modified carboxyl-terminal sequence KDEL which increases the toxin activity by 10 to 700 fold more potent than TP40 (TGFalpha-PE40)
Source
J Urol 1993 Jun;149(6):1626-32
Date of Entry
1993/06/28
Revision Date
2023/08/09
transforming growth factor(alpha)-Pseudomonas exotoxin A (35) Preferred
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