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tylosin reductase MeSH Supplementary Concept Data 2025


MeSH Supplementary
tylosin reductase
Unique ID
C082907
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C082907
Registry Numbers
EC 1.1.1.-
Heading Mapped to
*Alcohol Oxidoreductases
Frequency
2
Note
from Streptomyces fradiae; catalyzes the reduction of tylosin to relomycin in the presence of NADPH; MW 270 kDa; inhibited by FAD or FMN; shows a broad substrate specificity toward all macrolide aldehydes; may have physiological role of macrolide detoxification for the bacterium; structure of tylosin & relomycin given in first source
Source
J Biol Chem 1993 Sep 5;268(25):18987-93
Date of Entry
1993/09/27
Revision Date
1993/09/28
tylosin reductase Preferred
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